The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups¶
Why this mattered¶
TBD
Abstract¶
(no abstract available)
Related¶
- cite → Molecular portraits of human breast tumours — The 2,000-tumor breast-cancer study extends the molecular-subtype framework introduced by Perou's gene-expression portraits of breast tumors.
- cite → Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications — The 2012 METABRIC study extends the 2001 breast-cancer intrinsic gene-expression subtype framework by integrating genomic copy-number architecture with transcriptomic subgrouping.
- cite ← Comprehensive molecular portraits of human breast tumours — TCGA's breast cancer molecular portraits compare their integrated subtype findings with METABRIC's genomic and transcriptomic breast cancer subgroups.
- enables ← Molecular portraits of human breast tumours — The breast-tumor expression portraits introduced intrinsic molecular subtyping that METABRIC expanded with integrated genomic and transcriptomic data.
- enables ← Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications — The breast carcinoma subclass expression signatures provided clinically meaningful subtype concepts refined in the 2,000-tumor genomic architecture study.